منابع مشابه
BIOLOGICAL SCIENCES: Medical Sciences Pathogenetic mechanisms of AA amyloidosis Short title: Pathogenesis of AA amyloidosis
a Wolfson Drug Discovery Unit, Centre for Amyloidosis and Acute Phase Proteins, Division of Medicine, University College London, London NW3 2PF, UK; b Centre for Biomedical Science, Division of Medicine, University College London, London NW3 2PF, UK; Department of Molecular Medicine, University of Pavia, 27100 Pavia, Italy; d Centre for Neuroendocrinology, Division of Medicine, University Colle...
متن کاملRecent Insights into the Pathogenesis of Type AA Amyloidosis
The amyloidoses are a group of life-threatening diseases in which fibrils made of misfolded proteins are deposited in organs and tissues. The fibrils are stable, insoluble aggregates of precursor proteins that have adopted an antiparallel beta-sheet structure. In type AA, or reactive, amyloidosis, the precursor protein of the fibrils is serum amyloid A (SAA). SAA is a 104-amino-acid protein tha...
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ژورنال
عنوان ژورنال: Acta Medica Scandinavica
سال: 2009
ISSN: 0001-6101
DOI: 10.1111/j.0954-6820.1984.tb05009.x